In drug production, granulation is a key step in preparing solid preparations such as tablets and capsules. As an efficient and environmentally friendly granulation equipment, the pharmaceutical dry granulation machine has gradually become the preferred choice in the pharmaceutical industry due to its advantages of not requiring the addition of liquid adhesives and being suitable for thermosensitive drugs. This article will provide a detailed introduction to the working principle, advantages, application areas, and purchasing recommendations of pharmaceutical dry granulation machines.

1、 What is a medicinal dry granulation machine?

Pharmaceutical dry granulation machine is a device that directly compresses powdered pharmaceutical raw materials into granules through mechanical pressure. It does not require the addition of liquid adhesives, avoiding energy consumption and potential pollution in the drying process of wet granulation, and is particularly suitable for drug raw materials that are sensitive to heat or easily hydrolyzed.

2、 Advantages of pharmaceutical dry granulation machine

No need for liquid adhesive

Dry granulation does not require the addition of water or other solvents, avoiding degradation or chemical reactions of drug components, making it particularly suitable for thermosensitive drugs.

Efficient and energy-saving

Eliminating the drying process in wet granulation significantly reduces energy consumption and production time.

Environmentally friendly and pollution-free

No wastewater discharge, reducing environmental pollution, in line with the green environmental protection requirements of modern pharmaceutical production.

Improve drug stability

Dry granulation produces particles with high density and good flowability, which is beneficial for improving the stability and uniformity of drugs.

Strong adaptability

Suitable for various pharmaceutical raw materials, including drugs that are sensitive to heat, easily hydrolyzed, or insoluble.

3、 Application fields of medicinal dry granulation machine

tablet production

Intermediate particles used for preparing tablets to improve the compressibility and flowability of drugs.

Capsule filling

Make the medication into granules and fill them into capsules to ensure accurate dosage.

Traditional Chinese Medicine Preparations

Suitable for granulation of traditional Chinese medicine powder, improving its fluidity and solubility.

Functional drugs

Used for preparing drug particles in special dosage forms such as sustained-release and controlled release.

4、 How to choose a medicinal dry granulation machine?

material characteristics

Select appropriate equipment based on the fluidity, viscosity, particle size, and other characteristics of the drug raw materials.

production capacity

Select suitable models based on production scale to ensure that production needs are met.

Equipment material

Choose stainless steel materials that comply with GMP standards to ensure that the equipment is corrosion-resistant and easy to clean.

automaticity

Choose equipment equipped with automated control systems to improve production efficiency and consistency.

Supplier reputation

Choose suppliers with good reputation and rich experience to ensure equipment quality and after-sales service.

5、 The future development trend of pharmaceutical dry granulation machine

Intelligent

Realize intelligent control and data management of devices through the Internet of Things and artificial intelligence technology.

Efficient

Optimize equipment structure to improve production efficiency and energy utilization.

multi-functionality

Develop multifunctional dry granulation equipment suitable for various drug formulations.

The medicinal dry granulation machine has become an indispensable equipment in modern pharmaceutical production due to its high efficiency, environmental friendliness, and strong adaptability. By selecting the appropriate dry granulation machine, pharmaceutical companies can improve production efficiency, reduce energy consumption, and ensure drug quality, thereby gaining an advantage in the fiercely competitive market.

If you are looking for an efficient and environmentally friendly pharmaceutical dry granulation machine, please contact us! We provide high-quality equipment that meets GMP standards to help your drug production be more efficient and safe!