In the pharmaceutical industry, converting powdered raw materials into granules is a key step in producing solid formulations such as tablets and capsules. However, traditional wet granulation processes face many challenges:
High energy consumption: requires additional drying steps and consumes a large amount of energy.
Pollution risk: The use of liquid adhesives may introduce pollutants, affecting the quality of drugs.
Complex process: unfriendly to heat sensitive or easily hydrolyzed pharmaceutical raw materials.
The emergence of dry granulation machines provides efficient solutions to these challenges.
The dry granulation machine directly compresses powder raw materials into granules through mechanical pressure, without the need to add liquid binders. The workflow includes the following steps:
Mix the drug powder and excipients evenly to ensure ingredient consistency.
Press the powder into dense thin sheets or strips using high-pressure rollers.
Crush the pressed thin sheets or strips into particles of the desired size.
Separate the particles that meet the requirements through a sieve and collect them.
The dry granulation machine does not require drying steps, significantly shortening the production cycle.
The continuous production mode has increased production capacity and met the demand for large-scale drug production.
High particle density and good flowability improve the uniformity and stability of tablets or capsules.
No liquid adhesive is required, avoiding degradation or chemical reactions of drug components.
Reducing energy consumption and raw material waste has lowered production costs.
Equipment maintenance is simple, reducing operating costs.
No wastewater discharge, reducing environmental pollution.
Sealed design prevents dust from flying and ensures the safety of operators.
Suitable for various pharmaceutical raw materials, including drugs that are heat sensitive, easily hydrolyzed, or insoluble.
Can produce particles of different particle sizes to meet diverse formulation needs.
Intermediate particles used for preparing tablets to improve the compressibility and flowability of drugs.
Make the medication into granules and fill them into capsules to ensure accurate dosage.
Suitable for granulation of traditional Chinese medicine powder, improving its fluidity and solubility.
Used for preparing drug particles in special dosage forms such as sustained-release and controlled release.
Realize intelligent control and data management of devices through the Internet of Things and artificial intelligence technology.
Optimize equipment structure to improve production efficiency and energy utilization.
Develop a multifunctional dry granulation equipment suitable for multiple drug formulations.
Dry granulation machines, with their advantages of high efficiency, environmental friendliness, and strong adaptability, are changing the production mode of the pharmaceutical industry. By converting powder into particles, it not only improves drug production efficiency and quality, but also reduces costs and environmental pollution. With the continuous development of technology, dry granulation machines will play a more important role in the pharmaceutical industry.
If you are looking for an efficient and environmentally friendly dry granulation machine, please contact us! We provide high-quality equipment that meets GMP standards to help your drug production be more efficient and safe!
The dry granulation machine adopts the dry rolling process technology to compres
The machine is compliance with the GMP requirement on the production of pharmace
+Production DescriptionIndustrial 100kg 200kg 300kg Dry Powder Mixing Machine V
